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Ann-Shyn Chiang

Ph.D., RutgersUniversity, 1990

Tsing Hua Chair Professor & Director, Brain Research Center, National Tsing Hua University, 30013, Taiwan

International Faculty, Kavli Institute for Brain and Mind (KIBM) at the University of California, San Diego

email : aschiang@life.nthu.edu.tw
phone (886) 3-574-2760 


Research Interest: 

We aim to understand how genes and circuits orchestrate complex behavior in Drosophila.Three main approaches are taken: (i) to construct a brain-wide wiring diagram at single-cell resolution; (ii) to manipulate specific nodes in the circuits to understand how the brain encodes and decodes information; and (iii) to develop innovative technologies for functional connectomics research.

Selected Publications : 

  1. Lai JSY, Lo SJ, Dickson BJ and Chiang AS* (2012) An auditory circuit in the Drosophila brain. Proc Natl Acad Sci USA 109, 2607-2612.

  2. Chen CC, Wu JK, Lin HW, Pai TP, Fu TF, Wu CL, Tully T, Chiang AS* (2012) Visualizing long-term memory formation in two neurons of the Drosophila brain. Science 335, 678-685.

  3. Lee PT, Lin HW, Chang YH, Fu TF, Dubnau J, Hirsh J, Lee T and Chiang AS* (2011) A serotonin-mushroom body circuit modulating the formation of anesthesia-resistant memory in Drosophila. Proc Natl Acad Sci USA 108, 13794–13799.

  4. Wu CL, Shih MF Lai SY, Yang HT, Turner GC, Chen L, Chiang AS* (2011) Heterotypic gap junctions between two neurons in the Drosophila brain are critical for memory.Curr Biol 21, 848-854.

  5. Chiang AS*, Lin CY, Chuang CC, Chang HM, Hsieh CH, Yeh CW, Shih CT, Wu JJ, Wang GT, Chen YC, Wu CC, Chen GY, Ching YT, Lee PC, Lin CY, Lin HH, Wu CC, Hsu HW, Huang YA, Chen JY, Chiang HJ, Lu CF, Ni RF, Yeh CY, Hwang JK (2011) Three-dimensional reconstruction of brainwide wiring networks in Drosophila at single cell resolution. Curr Biol 21, 1-11.

  6. Lin HH, Lai JSY, Chin AL, Chen YC, Chiang AS* (2007) A map of olfactory representation in the Drosophila mushroom body. Cell 128, 1205-1217.

  7. Wu CL#, Xia S#, Fu TF, Wang H, Chen YH, Leong D, Chiang AS*, Tully T* (2007) Specific requirement of NMDA receptors for long-term memory consolidation in Drosophila ellipsoid body. Nat Neurosci 10, 1578-1586.

  8. Xia S, Miyashita T, Fu TF, Lin WY, Wu CL, Pyzocha L, Lin IR, Saitoe M, Tully T, Chiang AS* (2005) NMDA receptors mediate olfactory learning and memory in Drosophila. Curr Biol 15, 603-615.


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